Debiopharm, TCG Lifesciences complete first phase of research collaboration on discovery of new antibiotics

This first step towards identification of new classes of targeted anti-infectious drugs was achieved only 9 months after signature of a discovery collaboration will trigger the payment of research milestones by Debiopharm according to a pre-defined research plan.

Dr Saumitra Sengupta, Distinguished Scientist at TCG Lifesciences commented: "The strong collaborative spirit from both sides has resulted in reaching this important milestone. We are excited about partnering with Debiopharm in their search for new antibiotics and wish to continue in the same spirit of value addition in order to bring this project to a meaningful result."

"This fruitful collaboration with TCG Lifesciences has now delivered early leads ready to enter into the process of lead optimization", said Andrés McAllister, Chief Scientific Officer, Debiopharm International SA, who added: "It is an important milestone for Debiopharm, supporting our strong commitment to develop novel antibiotics to overcome resistance to current treatments.

It is part of our global strategy initiated with the development of our FabI inhibitors, Debio 1450, currently in clinical Phase I and Debio 1452 which has already demonstrated high efficacy in the treatment of acute bacterial skin and skin-structure infections in a phase II trial."